Just ran into a problem with IE10. I was unable to open a website with https protocol which have not trusted certificate by trusted root authorities.
In previous versions of IE it was possible to open such an page with warning but in IE10 I am only getting this error message without any option to open it instead.
Trigger the following command from the command prompt
certutil -setreg chain\EnableWeakSignatureFlags 8
N ow you will be presented the option to open the page again.